TL;DR. Titrate MAD to 3 mm over 4 weeks (Pépin 2025: −2.6% TST REMOV per mm). Add MFT ≥ 30 min/day (Guimarães core, top 5 exercises). Re-assess with formal PSG at week 10 scored for RERAs/RDI. Skip nasal strips unless you have real congestion. Mouth tape only if confirmed mouth breather. Phenotype ceiling is epiglottic — if plateau, escalation is CPAP/BiPAP/Inspire.
Full evidence base with tier 1–4 claim labels, primary-source verification log, grid of combinations, and protocol recommendation: pipelines/panthera-titration/INTERVENTION-STACK.md (local repo).
Generated 2026-04-16 · not medical advice · data in consumer metrics are proxies (Oura restless not PSG-validated) · use as decision support not prescription.